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Epistasis is fundamental to the structure and function of genetic pathways and to the evolutionary dynamics of complex genetic systems. High-throughput functional genomics, systems-level ...

Epistasis. Interestingly, the word “epistasis” is composed of Greek roots that mean “standing upon.” A good example of epistasis is coat color in the popular dog breed the Labrador retriever. Labrador retriever coat color genes。

We assessed the functional impact of the epistasis signals across a range of functional/-omics datasets identifying significant single-variant eQTLs across brain tissues,。

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